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Article Title: Over 100 Gaussia luciferase publications !
Date Posted: 2012-02-28

Gaussia luciferase, the brightest and smallest luciferase know so far is used by scientists in a broad range of applications.

Recently, Gaussia luciferase publications hit the 100 mark. We send our congratulations to all scientists using Gaussia.

Keep up the good work!


Publications of Gaussia luciferase as listed on

1: Cadete A, Figueiredo L, Lopes R, Calado CC, Almeida AJ, Gonçalves LM.
Development and characterization of a new plasmid delivery system based on
chitosan-sodium deoxycholate nanoparticles. Eur J Pharm Sci. 2012 Mar
12;45(4):451-8. Epub 2011 Oct 1. PubMed PMID: 21986445.

2: Ray P, Lewin SA, Mihalko LA, Lesher-Perez SC, Takayama S, Luker KE, Luker GD.
Secreted CXCL12 (SDF-1) forms dimers under physiological conditions. Biochem J.
2012 Mar 1;442(2):433-42. PubMed PMID: 22142194.

3: Song Y, Paul AV, Wimmer E. Evolution of poliovirus defective interfering
particles expressing gaussia luciferase. J Virol. 2012 Feb;86(4):1999-2010. Epub
2011 Dec 7. PubMed PMID: 22156535.

4: Huang W, Smaldino PJ, Zhang Q, Miller LD, Cao P, Stadelman K, Wan M, Giri B,
Lei M, Nagamine Y, Vaughn JP, Akman SA, Sui G. Yin Yang 1 contains G-quadruplex
structures in its promoter and 5'-UTR and its expression is modulated by G4
resolvase 1. Nucleic Acids Res. 2012 Feb 1;40(3):1033-49. Epub 2011 Oct 12.
PubMed PMID: 21993297; PubMed Central PMCID: PMC3273823.

5: Bovenberg MS, Degeling MH, Tannous BA. Enhanced gaussia luciferase blood assay
for monitoring of in vivo biological processes. Anal Chem. 2012 Jan
17;84(2):1189-92. Epub 2011 Dec 27. PubMed PMID: 22148161; PubMed Central PMCID:

6: Chaudhary A, Ganguly K, Cabantous S, Waldo GS, Micheva-Viteva SN, Nag K,
Hlavacek WS, Tung CS. The Brucella TIR-like protein TcpB interacts with the death
domain of MyD88. Biochem Biophys Res Commun. 2012 Jan 6;417(1):299-304. Epub 2011
Nov 29. PubMed PMID: 22155231.

7: Fick A, Lang I, Schäfer V, Seher A, Trebing J, Weisenberger D, Wajant H.
Studies of binding of tumor necrosis factor (TNF)-like weak inducer of apoptosis
(TWEAK) to fibroblast growth factor inducible 14 (Fn14). J Biol Chem. 2012 Jan
2;287(1):484-95. Epub 2011 Nov 11. PubMed PMID: 22081603; PubMed Central PMCID:

8: Wille T, Blank K, Schmidt C, Vogt V, Gerlach RG. Gaussia princeps luciferase
as a reporter for transcriptional activity, protein secretion, and
protein-protein interactions in Salmonella enterica serovar typhimurium. Appl
Environ Microbiol. 2012 Jan;78(1):250-7. Epub 2011 Oct 21. PubMed PMID: 22020521;
PubMed Central PMCID: PMC3255616.

9: Pietrella D, Enjalbert B, Zeidler U, Znaidi S, Rachini A, Vecchiarelli A,
d'Enfert C. A Luciferase Reporter for Gene Expression Studies and Dynamic Imaging
of Superficial Candida albicans Infections. Methods Mol Biol. 2012;845:537-46.
PubMed PMID: 22328402.

10: Tian W, Dong X, Liu X, Wang G, Dong Z, Shen W, Zheng G, Lu J, Chen J, Wang Y,
Wu Z, Wu X. High-throughput functional microRNAs profiling by recombinant
AAV-based microRNA sensor arrays. PLoS One. 2012;7(1):e29551. Epub 2012 Jan 5.
PubMed PMID: 22242174; PubMed Central PMCID: PMC3252342.

11: Donat S, Hasenberg M, Schäfer T, Ohlsen K, Gunzer M, Einsele H, Löffler J,
Beilhack A, Krappmann S. Surface display of Gaussia princeps luciferase allows
sensitive fungal pathogen detection during cutaneous aspergillosis. Virulence.
2012 Jan 1;3(1). [Epub ahead of print] PubMed PMID: 22286700.

12: Vecchiarelli A, d'Enfert C. Shedding natural light on fungal infections.
Virulence. 2012 Jan 1;3(1). [Epub ahead of print] PubMed PMID: 22286695.

13: Luker KE, Mihalko LA, Schmidt BT, Lewin SA, Ray P, Shcherbo D, Chudakov DM,
Luker GD. In vivo imaging of ligand receptor binding with Gaussia luciferase
complementation. Nat Med. 2011 Dec 4;18(1):172-7. doi: 10.1038/nm.2590. PubMed
PMID: 22138753; PubMed Central PMCID: PMC3253890.

14: Rathnayaka T, Tawa M, Nakamura T, Sohya S, Kuwajima K, Yohda M, Kuroda Y.
Solubilization and folding of a fully active recombinant Gaussia luciferase with
native disulfide bonds by using a SEP-Tag. Biochim Biophys Acta. 2011
Dec;1814(12):1775-8. Epub 2011 Sep 14. PubMed PMID: 21945374.

15: Hulleman JD, Kaushal S, Balch WE, Kelly JW. Compromised mutant EFEMP1
secretion associated with macular dystrophy remedied by proteostasis network
alteration. Mol Biol Cell. 2011 Dec;22(24):4765-75. Epub 2011 Oct 26. PubMed
PMID: 22031286; PubMed Central PMCID: PMC3237620.

16: Ray P, Lewin SA, Mihalko LA, Schmidt BT, Luker KE, Luker GD. Noninvasive
imaging reveals inhibition of ovarian cancer by targeting CXCL12-CXCR4.
Neoplasia. 2011 Dec;13(12):1152-61. PubMed PMID: 22241961; PubMed Central PMCID:

17: Laliberte JP, Weisberg AS, Moss B. The membrane fusion step of vaccinia virus
entry is cooperatively mediated by multiple viral proteins and host cell
components. PLoS Pathog. 2011 Dec;7(12):e1002446. Epub 2011 Dec 15. PubMed PMID:
22194690; PubMed Central PMCID: PMC3240603.

18: Kim SB, Suzuki H, Sato M, Tao H. Superluminescent variants of marine
luciferases for bioassays. Anal Chem. 2011 Nov 15;83(22):8732-40. Epub 2011 Oct
17. PubMed PMID: 21951281.

19: Bruning U, Fitzpatrick SF, Frank T, Birtwistle M, Taylor CT, Cheong A. NFκB
and HIF display synergistic behaviour during hypoxic inflammation. Cell Mol Life
Sci. 2011 Nov 9. [Epub ahead of print] PubMed PMID: 22068612.

20: Tannous BA, Teng J. Secreted blood reporters: insights and applications.
Biotechnol Adv. 2011 Nov-Dec;29(6):997-1003. Epub 2011 Sep 8. Review. PubMed
PMID: 21920429; PubMed Central PMCID: PMC3189544.

21: Kowalczuk L, Boudinet M, El Sanharawi M, Touchard E, Naud MC, Saïed A, Jeanny
JC, Behar-Cohen F, Laugier P. In vivo gene transfer into the ocular ciliary
muscle mediated by ultrasound and microbubbles. Ultrasound Med Biol. 2011
Nov;37(11):1814-27. Epub 2011 Oct 2. PubMed PMID: 21963032.

22: Kato M, Sasamori E, Chiba T, Hanyu Y. Cell activation by CpG ODN leads to
improved electrofusion in hybridoma production. J Immunol Methods. 2011 Oct
28;373(1-2):102-10. Epub 2011 Aug 22. PubMed PMID: 21878337.

23: Inoue Y, Sheng F, Kiryu S, Watanabe M, Ratanakanit H, Izawa K, Tojo A, Ohtomo
K. Gaussia luciferase for bioluminescence tumor monitoring in comparison with
firefly luciferase. Mol Imaging. 2011 Oct;10(5):377-85. doi:
10.2310/7290.2010.00057. Epub 2011 Apr 26. PubMed PMID: 21521553.

24: Kim SB, Takenaka Y, Torimura M. A bioluminescent probe for salivary cortisol.
Bioconjug Chem. 2011 Sep 21;22(9):1835-41. Epub 2011 Aug 22. PubMed PMID:

25: Kitai Y, Fukuda H, Enomoto T, Asakawa Y, Suzuki T, Inouye S, Handa H. Cell
selective targeting of a simian virus 40 virus-like particle conjugated to
epidermal growth factor. J Biotechnol. 2011 Sep 10;155(2):251-6. Epub 2011 Jul 1.
PubMed PMID: 21745502.

26: Du J, Tang Q, Huang Y, Rodney WE, Wang L, Liang G. Development of recombinant
rabies viruses vectors with Gaussia luciferase reporter based on Chinese vaccine
strain CTN181. Virus Res. 2011 Sep;160(1-2):82-8. Epub 2011 May 27. PubMed PMID:

27: Gil JS, Machado HB, Herschman HR. A Method to Rapidly and Accurately Compare
the Relative Efficacies of Non-invasive Imaging Reporter Genes in a Mouse Model
and its Application to Luciferase Reporters. Mol Imaging Biol. 2011 Aug 18. [Epub
ahead of print] PubMed PMID: 21850545.

28: Suzuki T, Kondo C, Kanamori T, Inouye S. Video rate bioluminescence imaging
of secretory proteins in living cells: localization, secretory frequency, and
quantification. Anal Biochem. 2011 Aug 15;415(2):182-9. Epub 2011 Apr 6. PubMed
PMID: 21477579.

29: Hashimoto T, Adams KW, Fan Z, McLean PJ, Hyman BT. Characterization of
oligomer formation of amyloid-beta peptide using a split-luciferase
complementation assay. J Biol Chem. 2011 Aug 5;286(31):27081-91. Epub 2011 Jun 7.
PubMed PMID: 21652708; PubMed Central PMCID: PMC3149301.

30: Inouye S, Sato J, Sahara-Miura Y. Recombinant Gaussia luciferase with a
reactive cysteine residue for chemical conjugation: expression, purification and
its application for bioluminescent immunoassays. Biochem Biophys Res Commun. 2011
Jul 15;410(4):792-7. Epub 2011 Jun 14. PubMed PMID: 21703234.

31: Zhu W, Li J, Tang L, Wang H, Li J, Fu J, Liang G. Glycoprotein is enough for
sindbis virus-derived DNA vector to express heterogenous genes. Virol J. 2011 Jul
10;8:344. PubMed PMID: 21740598; PubMed Central PMCID: PMC3148568.

32: Mahor S, Collin E, Dash BC, Pandit A. Controlled release of plasmid DNA from
hyaluronan nanoparticles. Curr Drug Deliv. 2011 Jul;8(4):354-62. PubMed PMID:

33: Badr CE, Wurdinger T, Tannous BA. Functional drug screening assay reveals
potential glioma therapeutics. Assay Drug Dev Technol. 2011 Jun;9(3):281-9. doi:
10.1089/adt.2010.0324. Epub 2010 Dec 27. PubMed PMID: 21184646; PubMed Central
PMCID: PMC3102258.

34: Marquardt A, Halle S, Seckert CK, Lemmermann NA, Veres TZ, Braun A, Maus UA,
Förster R, Reddehase MJ, Messerle M, Busche A. Single cell detection of latent
cytomegalovirus reactivation in host tissue. J Gen Virol. 2011 Jun;92(Pt
6):1279-91. Epub 2011 Feb 16. PubMed PMID: 21325477.

35: Huang R, Vider J, Serganova I, Blasberg RG. ATP-binding cassette transporters
modulate both coelenterazine- and D-luciferin-based bioluminescence imaging. Mol
Imaging. 2011 Jun;10(3):215-26. PubMed PMID: 21496450.

36: Niers JM, Kerami M, Pike L, Lewandrowski G, Tannous BA. Multimodal in vivo
imaging and blood monitoring of intrinsic and extrinsic apoptosis. Mol Ther. 2011
Jun;19(6):1090-6. Epub 2011 Feb 22. PubMed PMID: 21343914; PubMed Central PMCID:

37: Badr CE, Niers JM, Morse D, Koelen JA, Vandertop P, Noske D, Wurdinger T,
Zalloua PA, Tannous BA. Suicidal gene therapy in an NF-κB-controlled tumor
environment as monitored by a secreted blood reporter. Gene Ther. 2011
May;18(5):445-51. Epub 2010 Dec 9. PubMed PMID: 21150937.

38: Wang G, Dong X, Hu J, Tian W, Yuchi J, Wang Y, Wu X. Long-term ex vivo
monitoring of in vivo microRNA activity in liver using a secreted luciferase
sensor. Sci China Life Sci. 2011 May;54(5):418-25. Epub 2011 May 15. PubMed PMID:

39: Roda A, Cevenini L, Michelini E, Branchini BR. A portable bioluminescence
engineered cell-based biosensor for on-site applications. Biosens Bioelectron.
2011 Apr 15;26(8):3647-53. Epub 2011 Feb 18. PubMed PMID: 21388801.

40: Griesenbach U, Vicente CC, Roberts MJ, Meng C, Soussi S, Xenariou S, Tennant
P, Baker A, Baker E, Gordon C, Vrettou C, McCormick D, Coles R, Green AM, Lawton
AE, Sumner-Jones SG, Cheng SH, Scheule RK, Hyde SC, Gill DR, Collie DD, McLachlan
G, Alton EW. Secreted Gaussia luciferase as a sensitive reporter gene for in vivo
and ex vivo studies of airway gene transfer. Biomaterials. 2011
Apr;32(10):2614-24. Epub 2011 Jan 15. PubMed PMID: 21239054.

41: Takiguchi N, Takahashi Y, Nishikawa M, Matsui Y, Fukuhara Y, Oushiki D,
Kiyose K, Hanaoka K, Nagano T, Takakura Y. Positive correlation between the
generation of reactive oxygen species and activation/reactivation of transgene
expression after hydrodynamic injections into mice. Pharm Res. 2011
Apr;28(4):702-11. Epub 2010 Nov 30. PubMed PMID: 21116691.

42: Ganatra MB, Vainauskas S, Hong JM, Taylor TE, Denson JP, Esposito D, Read JD,
Schmeisser H, Zoon KC, Hartley JL, Taron CH. A set of aspartyl protease-deficient
strains for improved expression of heterologous proteins in Kluyveromyces lactis.
FEMS Yeast Res. 2011 Mar;11(2):168-78. doi: 10.1111/j.1567-1364.2010.00703.x.
Epub 2010 Dec 17. PubMed PMID: 21166768; PubMed Central PMCID: PMC3041862.

43: Dai T, Kharkwal GB, Zhao J, St Denis TG, Wu Q, Xia Y, Huang L, Sharma SK,
d'Enfert C, Hamblin MR. Ultraviolet-C light for treatment of Candida albicans
burn infection in mice. Photochem Photobiol. 2011 Mar-Apr;87(2):342-9. doi:
10.1111/j.1751-1097.2011.00886.x. Epub 2011 Feb 10. PubMed PMID: 21208209; PubMed
Central PMCID: PMC3048910.

44: Wen B, Deng Y, Guan J, Yan W, Wang Y, Tan W, Gao J. Signal peptide
replacements enhance expression and secretion of hepatitis C virus envelope
glycoproteins. Acta Biochim Biophys Sin (Shanghai). 2011 Feb;43(2):96-102. Epub
2010 Dec 31. PubMed PMID: 21196448.

45: He Y, Zhang WY, Gong M, Huang JY, Tang N, Feng T, Wei GH, He TC, Bi Y. Low
serum concentration facilitates the differentiation of hepatic progenitor cells.
Saudi Med J. 2011 Feb;32(2):128-34. PubMed PMID: 21301757.

46: Zhu W, Zhou J, Qin K, Du N, Liu L, Yu Z, Zhu Y, Tian W, Wu X, Shu Y. A
reporter system for assaying influenza virus RNP functionality based on secreted
Gaussia luciferase activity. Virol J. 2011 Jan 21;8:29. PubMed PMID: 21251302;
PubMed Central PMCID: PMC3039597.

47: Sharma R, Tsuchiya M, Tannous BA, Bartlett JD. Measurement of
fluoride-induced endoplasmic reticulum stress using Gaussia luciferase. Methods
Enzymol. 2011;491:111-25. PubMed PMID: 21329797.

48: Suzuki T, Kondo C, Kanamori T, Inouye S. Video-rate bioluminescence imaging
of matrix metalloproteinase-2 secreted from a migrating cell. PLoS One.
2011;6(9):e25243. Epub 2011 Sep 28. PubMed PMID: 21969874; PubMed Central PMCID:

49: Ellerkamp V, Armeanu-Ebinger S, Wenz J, Warmann SW, Schäfer J, Ruck P, Fuchs
J. Successful establishment of an orthotopic hepatoblastoma in vivo model in
NOD/LtSz-scid IL2Rγnull mice. PLoS One. 2011;6(8):e23419. Epub 2011 Aug 10.
PubMed PMID: 21853130; PubMed Central PMCID: PMC3154467.

50: Rathnayaka T, Tawa M, Sohya S, Yohda M, Kuroda Y. Biophysical
characterization of highly active recombinant Gaussia luciferase expressed in
Escherichia coli. Biochim Biophys Acta. 2010 Sep;1804(9):1902-7. Epub 2010 May 7.
PubMed PMID: 20452471.

51: Mehraein-Ghomi F, Basu HS, Church DR, Hoffmann FM, Wilding G. Androgen
receptor requires JunD as a coactivator to switch on an oxidative stress
generation pathway in prostate cancer cells. Cancer Res. 2010 Jun
1;70(11):4560-8. Epub 2010 May 11. PubMed PMID: 20460526; PubMed Central PMCID:

52: Chen F, Xu Z, Lu J, Lü X, Mu WL, Wang YJ, Liu DP, Liang CC. Gaussia
luciferase reporter assay for assessment of gene delivery systems in vivo. Chin
Med Sci J. 2010 Jun;25(2):95-9. PubMed PMID: 20598231.

53: Kimura T, Hiraoka K, Kasahara N, Logg CR. Optimization of enzyme-substrate
pairing for bioluminescence imaging of gene transfer using Renilla and Gaussia
luciferases. J Gene Med. 2010 Jun;12(6):528-37. PubMed PMID: 20527045; PubMed
Central PMCID: PMC2989363.

54: Ambolet-Camoit A, Bui LC, Pierre S, Chevallier A, Marchand A, Coumoul X,
Garlatti M, Andreau K, Barouki R, Aggerbeck M.
2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a
genotoxicant by upregulating expression of the metastasis marker agr2 in the
hepatocarcinoma cell line HepG2. Toxicol Sci. 2010 Jun;115(2):501-12. Epub 2010
Mar 18. PubMed PMID: 20299546.

55: Sharma R, Tsuchiya M, Skobe Z, Tannous BA, Bartlett JD. The acid test of
fluoride: how pH modulates toxicity. PLoS One. 2010 May 28;5(5):e10895. PubMed
PMID: 20531944; PubMed Central PMCID: PMC2878349.

56: Andreu N, Zelmer A, Fletcher T, Elkington PT, Ward TH, Ripoll J, Parish T,
Bancroft GJ, Schaible U, Robertson BD, Wiles S. Optimisation of bioluminescent
reporters for use with mycobacteria. PLoS One. 2010 May 24;5(5):e10777. PubMed
PMID: 20520722; PubMed Central PMCID: PMC2875389.

57: Feng B, Tomizawa K, Michiue H, Han XJ, Miyatake S, Matsui H. Development of a
bifunctional immunoliposome system for combined drug delivery and imaging in
vivo. Biomaterials. 2010 May;31(14):4139-45. Epub 2010 Feb 10. PubMed PMID:

58: d'Enfert C, Vecchiarelli A, Brown AJ. Bioluminescent fungi for real-time
monitoring of fungal infections. Virulence. 2010 May-Jun;1(3):174-6. PubMed PMID:

59: Lwa TR, Tan CH, Lew QJ, Chu KL, Tan J, Lee YY, Chao SH. Identification of
cellular genes critical to recombinant protein production using a Gaussia
luciferase-based siRNA screening system. J Biotechnol. 2010 Apr 15;146(4):160-8.
Epub 2010 Feb 25. PubMed PMID: 20188772.

60: Alexeyev MF, Fayzulin R, Shokolenko IN, Pastukh V. A retro-lentiviral system
for doxycycline-inducible gene expression and gene knockdown in cells with
limited proliferative capacity. Mol Biol Rep. 2010 Apr;37(4):1987-91. Epub 2009
Aug 5. PubMed PMID: 19655272; PubMed Central PMCID: PMC2832089.

61: Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M. piggyBac
transposon-mediated long-term gene expression in mice. Mol Ther. 2010
Apr;18(4):707-14. Epub 2010 Jan 26. PubMed PMID: 20104210; PubMed Central PMCID:

62: Patel KG, Ng PP, Kuo CC, Levy S, Levy R, Swartz JR. Cell-free production of
Gaussia princeps luciferase--antibody fragment bioconjugates for ex vivo
detection of tumor cells. Biochem Biophys Res Commun. 2009 Dec 18;390(3):971-6.
Epub 2009 Oct 21. PubMed PMID: 19852937.

63: Chung E, Yamashita H, Au P, Tannous BA, Fukumura D, Jain RK. Secreted Gaussia
luciferase as a biomarker for monitoring tumor progression and treatment response
of systemic metastases. PLoS One. 2009 Dec 15;4(12):e8316. PubMed PMID: 20016816;
PubMed Central PMCID: PMC2789383.

64: Welsh JP, Patel KG, Manthiram K, Swartz JR. Multiply mutated Gaussia
luciferases provide prolonged and intense bioluminescence. Biochem Biophys Res
Commun. 2009 Nov 27;389(4):563-8. PubMed PMID: 19825431.

65: Luo ST, Tian WH, Wang G, Dong XY, Yang L, Wu XB. [Comparison of TTR and CMV
promoters in vivo and in vitro via a secreted luciferase reporter system]. Bing
Du Xue Bao. 2009 Nov;25(6):424-9. Chinese. PubMed PMID: 20077932.

66: Enjalbert B, Rachini A, Vediyappan G, Pietrella D, Spaccapelo R, Vecchiarelli
A, Brown AJ, d'Enfert C. A multifunctional, synthetic Gaussia princeps luciferase
reporter for live imaging of Candida albicans infections. Infect Immun. 2009
Nov;77(11):4847-58. Epub 2009 Aug 17. PubMed PMID: 19687206; PubMed Central
PMCID: PMC2772526.

67: Tian W, Wang G, Luo S, Dong X, Fu X, Tan W, Wu X. [Real time ex vivo
detection and dynamic monitoring of in vivo expression of secreted luciferase
gene injected by hydrodynamic method]. Sheng Wu Gong Cheng Xue Bao. 2009
Oct;25(10):1552-7. Chinese. PubMed PMID: 20112701.

68: Badr CE, Niers JM, Tjon-Kon-Fat LA, Noske DP, Wurdinger T, Tannous BA.
Real-time monitoring of nuclear factor kappaB activity in cultured cells and in
animal models. Mol Imaging. 2009 Sep-Oct;8(5):278-90. PubMed PMID: 19796605;
PubMed Central PMCID: PMC2856067.

69: Maguire CA, Deliolanis NC, Pike L, Niers JM, Tjon-Kon-Fat LA, Sena-Esteves M,
Tannous BA. Gaussia luciferase variant for high-throughput functional screening
applications. Anal Chem. 2009 Aug 15;81(16):7102-6. PubMed PMID: 19601604; PubMed
Central PMCID: PMC2846205.

70: Serganova I, Moroz E, Vider J, Gogiberidze G, Moroz M, Pillarsetty N,
Doubrovin M, Minn A, Thaler HT, Massague J, Gelovani J, Blasberg R. Multimodality
imaging of TGFbeta signaling in breast cancer metastases. FASEB J. 2009
Aug;23(8):2662-72. Epub 2009 Mar 26. PubMed PMID: 19325038; PubMed Central PMCID:

71: Lerche K, Hallmann A. Stable nuclear transformation of Gonium pectorale. BMC
Biotechnol. 2009 Jul 10;9:64. PubMed PMID: 19591675; PubMed Central PMCID:

72: Luker K, Gupta M, Luker G. Bioluminescent CXCL12 fusion protein for cellular
studies of CXCR4 and CXCR7. Biotechniques. 2009 Jul;47(1):625-32. PubMed PMID:

73: Kim SB, Sato M, Tao H. Genetically encoded bioluminescent indicators for
stress hormones. Anal Chem. 2009 May 15;81(10):3760-8. PubMed PMID: 19388668.

74: Kaihara A, Sunami A, Kurokawa J, Furukawa T. A genetically encoded
bioluminescent indicator for the sodium channel activity in living cells. J Am
Chem Soc. 2009 Apr 1;131(12):4188-9. PubMed PMID: 19271706.

75: Kim HJ, Chung JK, Hwang do W, Lee DS, Kim S. In vivo imaging of miR-221
biogenesis in papillary thyroid carcinoma. Mol Imaging Biol. 2009
Mar-Apr;11(2):71-8. Epub 2008 Nov 22. PubMed PMID: 19030936.

76: Santos EB, Yeh R, Lee J, Nikhamin Y, Punzalan B, Punzalan B, La Perle K,
Larson SM, Sadelain M, Brentjens RJ. Sensitive in vivo imaging of T cells using a
membrane-bound Gaussia princeps luciferase. Nat Med. 2009 Mar;15(3):338-44. Epub
2009 Feb 15. PubMed PMID: 19219023; PubMed Central PMCID: PMC2837150.

77: Kim SB, Sato M, Tao H. Split Gaussia luciferase-based bioluminescence
template for tracing protein dynamics in living cells. Anal Chem. 2009 Jan
1;81(1):67-74. PubMed PMID: 19061336.

78: Yang J, Richmond AJ. Monitoring NF-kappaB mediated chemokine transcription in
tumorigenesis. Methods Enzymol. 2009;460:347-55. PubMed PMID: 19446734; PubMed
Central PMCID: PMC3140415.

79: Michelini E, Cevenini L, Mezzanotte L, Roda A. Luminescent probes and
visualization of bioluminescence. Methods Mol Biol. 2009;574:1-13. PubMed PMID:

80: Tannous BA. Gaussia luciferase reporter assay for monitoring biological
processes in culture and in vivo. Nat Protoc. 2009;4(4):582-91. PubMed PMID:
19373229; PubMed Central PMCID: PMC2692611.

81: Kim SB, Sato M, Tao H. Circularly permutated bioluminescent probes for
illuminating ligand-activated protein dynamics. Bioconjug Chem. 2008
Dec;19(12):2480-6. PubMed PMID: 19049389.

82: Takenaka Y, Masuda H, Yamaguchi A, Nishikawa S, Shigeri Y, Yoshida Y, Mizuno
H. Two forms of secreted and thermostable luciferases from the marine copepod
crustacean, Metridia pacifica. Gene. 2008 Dec 1;425(1-2):28-35. Epub 2008 Aug 7.
PubMed PMID: 18725274.

83: Asokan A, Johnson JS, Li C, Samulski RJ. Bioluminescent virion shells: new
tools for quantitation of AAV vector dynamics in cells and live animals. Gene
Ther. 2008 Dec;15(24):1618-22. Epub 2008 Jul 31. PubMed PMID: 18668144; PubMed
Central PMCID: PMC2684674.

84: Inouye S, Sahara Y. Soluble protein expression in E. coli cells using
IgG-binding domain of protein A as a solubilizing partner in the cold induced
system. Biochem Biophys Res Commun. 2008 Nov 21;376(3):448-53. Epub 2008 Sep 21.
PubMed PMID: 18789309.

85: Kim HJ, Kim YH, Lee DS, Chung JK, Kim S. In vivo imaging of functional
targeting of miR-221 in papillary thyroid carcinoma. J Nucl Med. 2008
Oct;49(10):1686-93. Epub 2008 Sep 15. PubMed PMID: 18794255.

86: Ketteler R, Seed B. Quantitation of autophagy by luciferase release assay.
Autophagy. 2008 Aug;4(6):801-6. Epub 2008 Jun 3. PubMed PMID: 18641457; PubMed
Central PMCID: PMC2910585.

87: Ruecker O, Zillner K, Groebner-Ferreira R, Heitzer M. Gaussia-luciferase as a
sensitive reporter gene for monitoring promoter activity in the nucleus of the
green alga Chlamydomonas reinhardtii. Mol Genet Genomics. 2008 Aug;280(2):153-62.
Epub 2008 May 31. PubMed PMID: 18516621.

88: Shao N, Bock R. A codon-optimized luciferase from Gaussia princeps
facilitates the in vivo monitoring of gene expression in the model alga
Chlamydomonas reinhardtii. Curr Genet. 2008 Jun;53(6):381-8. Epub 2008 Apr 12.
PubMed PMID: 18408930; PubMed Central PMCID: PMC2413079.

89: Hewett JW, Nery FC, Niland B, Ge P, Tan P, Hadwiger P, Tannous BA, Sah DW,
Breakefield XO. siRNA knock-down of mutant torsinA restores processing through
secretory pathway in DYT1 dystonia cells. Hum Mol Genet. 2008 May
15;17(10):1436-45. Epub 2008 Feb 7. PubMed PMID: 18258738; PubMed Central PMCID:

90: Goerke AR, Loening AM, Gambhir SS, Swartz JR. Cell-free metabolic engineering
promotes high-level production of bioactive Gaussia princeps luciferase. Metab
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